Re-irradiation for recurrent rhabdomyosarcoma of the nasopharynx in a child

There are few clinical situations where high dose re-irradiation with curat ive intent is indicated in children. Because of the potential for serious l ate sequelae, re-irradiation is considered only in the unusual situation wh ere there is just local recurrence and surgery and/or chemotherapy are unli kely to provide long-term control. The authors present a case of nasopharyn x rhabdomyosarcoma in a child which recurred after high dose irradiation an d chemotherapy and was then re-irradiated to a high dose. The child is well without any serious sequelae more than 13 years following completion of th e second course of radiotherapy. (C) 1999 Elsevier Science Ltd. All rights reserved.