DNA binding alkaloids from Prosopis alba

Authors
Astudillo, L Jurgens, K Schmeda-Hirschmann, G Griffith, GA Holt, DJ Jenkins, PR
Citation
L. Astudillo et al., DNA binding alkaloids from Prosopis alba, PLANTA MED, 65(2), 1999, pp. 161-162
Citations number
12
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943 → ACNP
Volume
65
Issue
2
Year of publication
1999
Pages
161 - 162
Database
ISI
SICI code
0032-0943(199903)65:2<161:DBAFPA>2.0.ZU;2-H
Abstract
The known beta-phenethylamine (1) and the new alkaloid 2-beta-methyl-3-beta -hydroxy-6-beta-piperidinedodecanol (2) were isolated from the aerial parts of Prosopis alba. Both compounds showed DNA binding effects of 27 and 50%, respectively, at 0.50 mg/ml.