Primary cerebral lymphoma: three case-reports

Primary lymphomas of the central nervous system (CNS) contribute only 1 to 2% of all lymphomas and 0.5 to 1% of all CNS tumors. Three cases are report ed in patients admitted for intracranial hypertension and focal neurologic signs. Computed tomography of the brain showed a space-occupying lesion in all three cases. Location was a cerebral hemisphere in two eases and the op tic chiasma in one. A surgical biopsy was done in all three cases, and hist ologic findings indicated a B-cell lymphoma. Staging investigations were ne gative. Two patients had chemotherapy and radiotherapy. The diagnosis and p rognosis of primary CNS lymphomas are discussed.