SYNTHETIC STUDIES TOWARDS COMPLEX DITERPENOIDS .19. TOTAL SYNTHESIS OF (PLUS-OR-MINUS)-DEOXOFAVELINE, (PLUS-OR-MINUS)-FAVELINE METHYL-ETHERAND (PLUS-OR-MINUS)-FAVELINE

Authors
GHOSH AK MUKHOPADHYAY C GHATAK UR
Citation
Ak. Ghosh et al., SYNTHETIC STUDIES TOWARDS COMPLEX DITERPENOIDS .19. TOTAL SYNTHESIS OF (PLUS-OR-MINUS)-DEOXOFAVELINE, (PLUS-OR-MINUS)-FAVELINE METHYL-ETHERAND (PLUS-OR-MINUS)-FAVELINE, Journal of the Chemical Society. Perkin transactions. I, (3), 1994, pp. 327-332
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
3
Year of publication
1994
Pages
327 - 332
Database
ISI
SICI code
0300-922X(1994):3<327:SSTCD.>2.0.ZU;2-T
Abstract
Simple and efficient syntheses have been developed for the cytotoxic d inorditerpenoids, deoxofaveline 1. (+/-)-faveline methyl ether 2 and ( +/-)-faveline 3, having a hexahydrodibenzo[a,d]cycloheptene ring syste m. through the enolizable tricyclic ketone mixture 12 and 13, prepared from the easily accessible 2-arylethyl-3,3-dimethylcyclohexanone 7.