A new synthesis of alkyl 1-alkyl-2-methylpyrrole-3-carboxylates by ring transformation of 2-chloro-2-acetimidoylbutyrolactones

Authors
Kesteleyn, B Alonso, ER Stevens, C Dejaegher, Y Peristeropoulou, M Van, TN Kulinkovich, O De Kimpe, N
Citation
B. Kesteleyn et al., A new synthesis of alkyl 1-alkyl-2-methylpyrrole-3-carboxylates by ring transformation of 2-chloro-2-acetimidoylbutyrolactones, TETRAHEDRON, 55(13), 1999, pp. 4153-4166
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
13
Year of publication
1999
Pages
4153 - 4166
Database
ISI
SICI code
0040-4020(19990326)55:13<4153:ANSOA1>2.0.ZU;2-S
Abstract
Reaction of 2-chloro-2-acetimidoylbutyrolactones with sodium methoxide or s odium ethoxide in the corresponding alcohol provides a facile one-step synt hesis of methyl or ethyl 1-alkyl-2-methylpyrrole-3-carboxylates from readil y available starting materials. (C) 1999 Elsevier Science Ltd. All rights r eserved.