Diastereoselective alkynylation of chiral non-racemic oxazolidines with mixed organoaluminum compounds

Authors
Blanchet, J Bonin, M Chiaroni, A Micouin, L Riche, C Husson, HP
Citation
J. Blanchet et al., Diastereoselective alkynylation of chiral non-racemic oxazolidines with mixed organoaluminum compounds, TETRAHEDR L, 40(15), 1999, pp. 2935-2938
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
15
Year of publication
1999
Pages
2935 - 2938
Database
ISI
SICI code
0040-4039(19990409)40:15<2935:DAOCNO>2.0.ZU;2-4
Abstract
A new efficient and scalable route to chiral non-racemic alpha-substituted propargylamines is described. The reaction pathway consists of the diastere oselective addition of mixed alkynylaluminum reagents to oxazolidines deriv ed from R-()-phenylglycinol, (C) 1999 Published by Elsevier Science Ltd. Al l rights reserved.