Studies on the total synthesis of the saponaceolides. 1. Enantioselective synthesis of the spiroketal subunit

Authors
Vidari, G Lanfranchi, G Pazzi, N Serra, S
Citation
G. Vidari et al., Studies on the total synthesis of the saponaceolides. 1. Enantioselective synthesis of the spiroketal subunit, TETRAHEDR L, 40(15), 1999, pp. 3063-3066
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
15
Year of publication
1999
Pages
3063 - 3066
Database
ISI
SICI code
0040-4039(19990409)40:15<3063:SOTTSO>2.0.ZU;2-X
Abstract
An asymmetric synthesis of the tricyclic spiroketal subunit of the saponace olides is described in which the absolute stereochemistry at C-2' and C-6' is established through a conformationally and stereoelectronically controll ed cyclization of a dihydroxyketone pyran Intermediate. (C) 1999 Elsevier S cience Ltd. All rights reserved.