Studies on the total synthesis of the saponaceolides. 2. Enantioselective synthesis of 2-epi-saponaceolide B

Authors
Vidari, G Pazzi, N Lanfranchi, G Serra, S
Citation
G. Vidari et al., Studies on the total synthesis of the saponaceolides. 2. Enantioselective synthesis of 2-epi-saponaceolide B, TETRAHEDR L, 40(15), 1999, pp. 3067-3070
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
15
Year of publication
1999
Pages
3067 - 3070
Database
ISI
SICI code
0040-4039(19990409)40:15<3067:SOTTSO>2.0.ZU;2-T
Abstract
The paper describes an asymmetric convergent synthesis of 2-epi-saponaceoli de B, illustrating a general approach to the construction of the saponaceol ide structure. The strategic C10'-C11' bond was formed by coupling a lithiu m salt containing the left part of the molecule with a carbonyl derivative representing the right part. (C) 1999 Elsevier Science Ltd. All rights rese rved.