G. Vidari et al., Studies on the total synthesis of the saponaceolides. 2. Enantioselective synthesis of 2-epi-saponaceolide B, TETRAHEDR L, 40(15), 1999, pp. 3067-3070
The paper describes an asymmetric convergent synthesis of 2-epi-saponaceoli
de B, illustrating a general approach to the construction of the saponaceol
ide structure. The strategic C10'-C11' bond was formed by coupling a lithiu
m salt containing the left part of the molecule with a carbonyl derivative
representing the right part. (C) 1999 Elsevier Science Ltd. All rights rese
rved.