Stereoselective Grignard-type reactions of chiral N,N-dibenzylamino ketones

Authors
Reetz, MT Schmitz, A
Citation
Mt. Reetz et A. Schmitz, Stereoselective Grignard-type reactions of chiral N,N-dibenzylamino ketones, TETRAHEDR L, 40(14), 1999, pp. 2737-2740
Citations number
30
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
14
Year of publication
1999
Pages
2737 - 2740
Database
ISI
SICI code
0040-4039(19990402)40:14<2737:SGROCN>2.0.ZU;2-7
Abstract
N-N-Dibenzylamino ketones of the type Bn2N(R-1)CHC(O)R-2, prepared in enant iomerically pure form from alpha-amino acids, undergo non-chelation control led Grignard-type reactions with RLi, RMgX or RCeCl2 without any undesired racemization. (C) 1999 Elsevier Science Ltd. All rights reserved.