Construction of chiral quaternary carbon centers by asymmetric alkylation of achiral lithium enolates mediated by chiral tetradentate ligands: Stoichiometric and catalytic approaches

Authors
Yamashita, Y Odashima, K Koga, K
Citation
Y. Yamashita et al., Construction of chiral quaternary carbon centers by asymmetric alkylation of achiral lithium enolates mediated by chiral tetradentate ligands: Stoichiometric and catalytic approaches, TETRAHEDR L, 40(14), 1999, pp. 2803-2806
Citations number
20
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
14
Year of publication
1999
Pages
2803 - 2806
Database
ISI
SICI code
0040-4039(19990402)40:14<2803:COCQCC>2.0.ZU;2-G
Abstract
Enantioselective asymmetric alkylation of achiral lithium enolates mediated by chiral tetradentate amine ligands is achieved to give chiral quaternary carbon centers. Turnover of a chiral tetradentate amine in the presence of an achiral bidentate amine during the reaction is also realized. (C) 1999 Elsevier Science Ltd. All rights reserved.