Moonlighting proteins

Authors
Citation
Cj. Jeffery, Moonlighting proteins, TRENDS BIOC, 24(1), 1999, pp. 8-11
Citations number
27
Categorie Soggetti
Biochemistry & Biophysics
Journal title
TRENDS IN BIOCHEMICAL SCIENCES
ISSN journal
09680004 → ACNP
Volume
24
Issue
1
Year of publication
1999
Pages
8 - 11
Database
ISI
SICI code
0968-0004(199901)24:1<8:MP>2.0.ZU;2-6
Abstract
The idea of one gene - one protein - one function has become too simple bec ause increasing numbers of proteins are found to have two or more different functions. The multiple functions of such moonlighting proteins add anothe r dimension to cellular complexity and benefit cells in several ways. Howev er, cells have had to develop sophisticated mechanisms for switching betwee n the distinct functions of these proteins.