Citation
Pl. Chang et al., The in vivo delivery of heterologous proteins by microencapsulated recombinant cells, TRENDS BIOT, 17(2), 1999, pp. 78-83
Citations number
41
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
TRENDS IN BIOTECHNOLOGY
ISSN journal
01677799
→ ACNP
Volume
17
Issue
2
Year of publication
1999
Pages
78 - 83
Database
ISI
SICI code
0167-7799(199902)17:2<78:TIVDOH>2.0.ZU;2-8
Abstract
The microencapsulation of recombinant cells is a novel and potentially cost
-effective method of heterologous protein delivery, A 'universal' cell line
, genetically modified to secrete any desired protein, is immunologically p
rotected from tissue rejection by enclosure in microcapsules. The microcaps
ule can then be implanted in different recipients to deliver recombinant pr
oteins in vivo.