We describe a case of fetal rhabdomyosarcoma detected during the third trim
ester of pregnancy by prenatal sonography. At 33 weeks' gestation, sonograp
hy performed because of suspected polyhydramnios showed a solid mass of 120
x 54 mm arising from the anterior wall of the fetal thoracic cage. Another
mass within the left maxillary area which originated from the left orbital
floor was also detected. In the abdomen, there were multiple round masses
in and around the liver. As the previous scan at 28 weeks had appeared norm
al, the multiple masses which became visible and enlarged rapidly in differ
ent locations led us to believe that there was fetal cancer. The most likel
y diagnosis was rhabdomyosarcoma (which was later confirmed), because it is
the most prevalent soft-tissue tumor in children and may develop within or
outside muscle anywhere in the body and at any age. Two other reported cas
es which were detected by prenatal ultrasound examination are also discusse
d.