SOLVATOCHROMICALLY BASED SOLVENT-SELECTIVITY TRIANGLE

A classification of common solvents according to their dipolarity and hydrogen-bonding acidity and basicity has been developed, based on the Kamlet-Taft solvatochromic parameter scheme. This approach has been c ompared with the Snyder-Rohrschneider solvent-selectivity triangle (SS T). The two solvent-classification schemes are found to be generally s imilar. Both SST-based schemes are also compared to an analysis of sol vent selectivity based on linear solvation energy relationships. While there are considerable similarities, important practical differences, especially in the case of reversed-phase liquid chromatography, are e vident.