LOW IMMUNOGLOBULIN-G3 LEVELS IN WHEEZY CHILDREN

Authors
ONES U GULER N SOMER A SALMAN N YALCIN I
Citation
U. Ones et al., LOW IMMUNOGLOBULIN-G3 LEVELS IN WHEEZY CHILDREN, Acta paediatrica, 87(4), 1998, pp. 368-370
Citations number
16
Categorie Soggetti
Pediatrics
Journal title
Acta paediatrica → ACNP
ISSN journal
08035253
Volume
87
Issue
4
Year of publication
1998
Pages
368 - 370
Database
ISI
SICI code
0803-5253(1998)87:4<368:LILIWC>2.0.ZU;2-O
Abstract
This study aimed to investigate the prevalence of IgG subclass deficie ncy in wheezy children aged <3 y. Serum levels of IgA, IgE and IgG sub classes were measured in 310 children with recurrent wheezing and in 1 00 healthy controls. IgG3 levels were below the normal lower limit in 123 (39.6%) patients. This finding may reflect delayed maturation of t he immune system, predisposing young children <3 y of age to wheezing.