A survey was undertaken to evaluate compliance in Spanish patients rec
eiving growth hormone treatment. The 28-item structured questionnaire
was designed to collect data on compliance, treatment schedule, device
used and instruction received. In total, 473 questionnaires were comp
leted in 17 paediatric endocrine units. Compliance was divided into fo
ur categories based on percentage of doses omitted, classified as exce
llent if 0%, good <5%, fair 5-10% and poor >10%. The level of complian
ce was excellent in 74.0%, good in 20.1%, fair in 3.4% and poor in 2.5
%. Compliance was better in those who injected themselves (p < 0.01),
were trained by hospital staff (p < 0.01) and used automatic pens (p <
0.05). Patients using conventional syringes were less Likely to compl
y (p < 0.05). More information on growth hormone treatment was request
ed by 57.6% of patients. The results indicate that the specialist nurs
e should spend sufficient time with the patients and relatives to ensu
re a higher compliance rate.