MOLECULAR MECHANISMS OF SEPSIS

Authors
WOLTMANN A HAMANN L ULMER AJ GERDES J BRUCH HP RIETSCHEL ET
Citation
A. Woltmann et al., MOLECULAR MECHANISMS OF SEPSIS, LANGENBECKS ARCHIVES OF SURGERY, 383(1), 1998, pp. 2-10
Citations number
80
Categorie Soggetti
Surgery
Journal title
LANGENBECKS ARCHIVES OF SURGERY → ACNP
ISSN journal
14352443
Volume
383
Issue
1
Year of publication
1998
Pages
2 - 10
Database
ISI
SICI code
1435-2443(1998)383:1<2:MMOS>2.0.ZU;2-2
Abstract
Today a great number of problems in the field of bacterial sepsis rema in to be solved. Understanding the molecular mechanisms of one of the most important bacterial products in the pathogenesis of sepsis - endo toxin may contribute to innovative and more effective therapies. There fore, this review focuses on the structural and functional elements of endotoxin, its interaction with immune cells? and its biological acti vity. Finally, other bacterial components and their impact on sepsis a re discussed.