J. Holtzman et al., THE EFFECTS OF CLINICAL PATHWAYS FOR RENAL-TRANSPLANT ON PATIENT OUTCOMES AND LENGTH OF STAY, Medical care, 36(6), 1998, pp. 826-834
OBJECTIVES. Clinical pathways have been implemented nationwide but lit
tle is understood about their effects on efficiency of care and patien
t outcomes. The present study examined the effects of both development
and implementation of two renal transplant pathways. METHODS. Cohorts
of patients at a university hospital were compared before, during, an
d after the development and implementation of two renal transplant cli
nical pathways: isolated renal transplant from cadaveric donors (n = 1
70) or from living donors (n = 178). Clinical pathways for cadaveric a
nd living related donor renal transplants were developed and implement
ed. Hospital length of stay and complications and infections after ren
al transplant were determined. RESULTS. Mean length of hospital stay d
ecreased after development and implementation of the cadaveric donor p
athway (11.8 days after implementation versus 17.5 days before develop
ment). Cadaveric kidney recipients also had statistically fewer compli
cations and infections after both guideline development and guideline
implementation (57.1% before, 24.5% during, 18.5% after), but the grea
test effect occurred during development. All of these findings persist
ed after control for demographic and comorbid factors. There were no c
hanges in hospital stay, complications, or infections in the patients
who received kidneys from living donors. CONCLUSIONS. The development
and use of a clinical pathway for cadaveric donor renal transplant pat
ients was associated with a significant decline in length of stay, com
plications, and infections, but much of the effect was seen during dev
elopment rather than during implementation, and a closely related path
way for living related donor patients had no effect. Further understan
ding of what factors predict an effective pathway and what elements (i
e, development or implementation) have an effect should be undertaken.