ACCELERATION OF THE PENETRATION OF RABIES VIRUS VACCINATION STRAIN VNUKOVO-32 BY DEAE-DEXTRAN AT ORAL-ADMINISTRATION TO SUCKLING MICE

Authors
ONDREJKA R SVRCEK S BENISEK Z DUROVE A SULIOVA J
Citation
R. Ondrejka et al., ACCELERATION OF THE PENETRATION OF RABIES VIRUS VACCINATION STRAIN VNUKOVO-32 BY DEAE-DEXTRAN AT ORAL-ADMINISTRATION TO SUCKLING MICE, Veterinarni medicina, 43(5), 1998, pp. 161-163
Citations number
16
Categorie Soggetti
Veterinary Sciences
Journal title
Veterinarni medicina → ACNP
ISSN journal
03758427
Volume
43
Issue
5
Year of publication
1998
Pages
161 - 163
Database
ISI
SICI code
0375-8427(1998)43:5<161:AOTPOR>2.0.ZU;2-8
Abstract
The influence of DEAE-dextran on acceleration of the penetration of Vn ukovo-32 vaccination strain was investigated in oral application exper iments on suckling mice. The method of cryostat sections of organs and sections stained by the direct immunofluorescence method for detectio n of rabies antigen was used. The results of experiments confirmed tha t DEAE-dextran has an accelerating effect on the penetration of attenu ated vaccination strain of rabies virus. Conditions for utilization of this knowledge for oral antirabies vaccination have been created.