EFFECT OF ENDURANCE TRAINING ON OXIDATION OF LACTATE IN MICE AFTER SUPRAMAXIMAL EXERCISE

The effect of endurance training on lactate metabolism after supramaxi mal exercise was investigated in male ddY mice. The blood lactate conc entration 20 min after supramaximal exercise in the trained mice was s ignificantly lower than that in the control mice. No significant effec t of endurance training on the amount of (CO2)-C-14 expired from [C-14 ]lactate injected was found during the recovery period from supramaxim al exercise. The muscle [C-14]glycogen concentration after 20 min of r ecovery in the trained mice was significantly higher than that in the control mice. These results suggest that endurance training does not e nhance oxidative removal of lactate, which is the most important pathw ay of lactate metabolism, and activates muscle glycogen resynthesis fr om lactate in mice after supramaximal exercise.