XY-4-NITROPHENYL)-2-(3,4,5-TRIMETHOXYPHENYL)ETHENE

The design and synthesis of new photoaffinity labeling (PAL) reagents is important in order to obtain detailed binding-site and structural i nformation about tubulin, y-4-nitrophenyl)-2-(3,4,5-trimethoxyphenyl)e thene, C18H19NO6, crystallizes in the centrosymmetric space group P2(1 )/n (No. 14), with four molecules in the unit cell. The trans-stilbene base component is nearly planar (mean deviation 0.05 Angstrom), with a dihedral angle between the two phenyl rings of 6.1 degrees. Importan t bond distances include C=C 1.326(3) Angstrom and mean N-O 1.187(8)An gstrom.