Background. The results of saphenectomy in patients with morphologic a
nd functional obstruction were compared with those in patients without
obstruction. Excision of secondary saphenous varices associated with
deep venous obstruction has long been considered contraindicated for f
ear of compromising its collateral contribution. Recent advances in ac
curate functional assessment of venous obstruction maize it possible t
o test this concept. Methods. Saphenectomy was carried out in 51 limbs
without morphologic or functional obstruction and 64 limbs with varyi
ng grades of venous obstruction. Significant deep venous obstruction o
n ascending venography was present in the latter group. Functional ass
essment of obstruction was based on the arm/foot venous pressure diffe
rential technique, outflow fraction measurements, and outflow resistan
ce calculations. Valve reconstruction was carried out in conjunction w
ith saphenectomy in 81% Of Cases. Results. Saphenectomy was clinically
well tolerated in both groups, and there was no difference in outcome
as measured by objective tests for obstruction; improvement in reflux
and calf venous pump function was largely similar Among seven limbs w
ith severe preoperative venous obstruction (grade III or IV), five (70
%) had significantly improved obstructive grading, presumably as a res
ult of elimination of reflux flow. Conclusions. The traditional admoni
tion against removal of secondary varices should be reexamined. Saphen
ectomy may be indicated in postthrombotic syndrome with mixed obstruct
ion/reflux. The procedure is clinically well tolerated and without mal
sequelae. Improvement in reflux parameters without significant worseni
ng of objective measures of obstruction is documented in this group.