S. Mariethoz et al., SPLENIC VEIN-THROMBOSIS AND CHRONIC-PANCR EATITIS - THERAPEUTIC APPROACH, Schweizerische medizinische Wochenschrift, 128(22), 1998, pp. 867-870
10% of chronic pancreatitis (CP) cases are complicated by splenic vein
thrombosis (SVT) which is responsible for upper digestive haemorrhage
s. To improve our approach to treatment we reviewed 30 cases of SVT as
sociated with CP treated in our centre from 1985 to 1995. 14 patients
were treated conservatively. Six of them were refused for surgery due
to extension of splenic vein thrombosis into the portal vein. Two pati
ents without extrinsic compression of the vein were treated with antic
oagulants. 16 patients were treated by surgery with low morbidity and
without mortality. The standard treatment in fourteen cases was spleno
pancreatectomy. The average follow-up of seven years shows that these
patients have preserved their body mass index (BMI). The results sugge
st that early surgical intervention is beneficial in preventing progre
ssion of SVT to the portomesenteric vein.