Purpose: To assess the feasibility and diagnostic performance of lung
transthoracic sonography in patients with suspected pulmonary embolism
. Method: In a prospective clinical study we compared sonographic find
ings of the peripheral lung with various scintigraphic gradings and D-
dimer plasma concentrations. One hundred and nineteen consecutive pati
ents with clinical signs of pulmonary embolism were investigated withi
n 24 hours of the onset of symptoms. Results: Seventy patients with su
spected pulmonary embolism (59%) had sonographic lesions, which were e
cho poor, homogeneous and rounded or wedge-shaped with a hyperechoic r
eflexion in the centre. Of the patients with high-probability scintigr
aphic scans 86% had such sonographic lesions as had 79% with intermedi
ate, 64% with low-probability and 33% with normal scintigraphic scans.
Of the patients with positive sonographic findings and normal or low-
probability scans only a minority (14%) had negative D-dimer tests. Co
nclusion: We found a high rate of specific sonographic lesions in pati
ents with suspected pulmonary embolism when investigating the peripher
al lung with ultrasound.