Ad. Vrachatis et al., ORIGIN AT ANGINA-PECTORIS IN PATIENTS WITH HIGH-GRADE SINGLE-VESSEL CORONARY-ARTERY STENOSIS UNDERGOING PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, The American journal of cardiology, 81(11), 1998, pp. 1345
This study shows that in patients with subtotal (95% to 99%) coronary
artery stenosis, the presence of myocardial ischemia is dictated prima
rily by the presence and degree of coronary collateral how, with anter
ograde flow participating little, if at all, in the origin of myocardi
al ischemia and angina pectoris. Conversely, in patients with severe b
ut not subtotal coronary artery stenosis (70% to 94%), both reduced an
terograde flow and coronary collateralization contribute to the evolut
ion of myocardial ischemia and angina pectoris.