Following successful RF ablation of the atrioventricular node IA (AVN)
, temporary pacing is necessary prior to insertion of a permanent pace
maker. The risks and inconvenience of temporary pacing could be avoide
d if a permanent pacemaker is already in place. This study reports the
feasibility of RF ablation of the AVN in 27 patients (age 55 +/- 17 y
ears, 15 males) with hypertrophic cardiomyopathy and pacemakers. Indic
ations for AVN ablation were drug refractory atrial fibrillation in 24
patients, and rapid AVN conduction preventing septal pre-excitation b
y DDD pacemaker, inserted for relief of left ventricular outflow obstr
uction, in three cases. Sixteen patients had DDD devices and 11 patien
ts had WI devices. During RF ablation, each pacemaker was programmed t
o WI at 50 beats/min. The ablation catheter was manipulated with fluor
oscopic control to avoid close contact with or disturbance of the paci
ng leads. In 16 patients, RF ablation was performed immediately follow
ing pacemaker implantation but in the remaining patients, the AVN was
ablated 6-32 months after pacemaker implantation. The power applied wa
s 25-50 watts for a duration of 15-60 seconds. AV block was achieved i
n all cases but required 34 +/- 36 applications for 16.5 +/- 17.8 min/
case. RF ablation consistently caused reversion to magnet rate in one
patient and temporarily inhibited appropriate pacemaker discharge in a
nother. However, no other pacemaker or lead malfunction was detected s
o that temporary pacing wets not required in any case. At 6 +/- 3 mont
hs follow-up, all pacemakers were functioning normally without alterat
ion in pacing parameters from baseline. Thus, RF ablation of the AVN c
an be performed safely in the presence of a recently implanted permane
nt pacemaker, without temporary pacing.