Objective: To determine whether three-dimensional ultrasonography can
increase the ability to evaluate the ovary and follicles, especially i
n women with polycystic ovary disease (PCOD). Design: Prospective clin
ical study. Setting: University hospital endocrine and infertility cen
ter. Patient(s): Sixty-six patients undergoing routine gynecologic eva
luation were divided into two groups: the normal control group consist
ed of 22 patients, and there were 44 patients with PCOD. Intervention(
s): Three-dimensional ultrasonography was performed to store and docum
ent whole volumes of the ovaries for evaluation. Main Outcome Measure(
s): Three perpendicular planes of bilateral ovaries are rotatable to o
btain the largest dimensions. The three-dimensional volume was measure
d using the trapezoid formula Result(s): The ovaries of the patients w
ith PCOD were larger in size, area, and volume than those of normal co
ntrols. Conclusion(s): Stroma and volume determinations can be obtaine
d more accurately by three-dimensional images than by traditional ultr
asonography. Three-dimensional ultrasonography not only facilitates no
ninvasive evaluation and volume calculation but also completes the exa
mination in a short time without increasing patient discomfort. (C)199
8 by American Society for Reproductive Medicine.