Several epidemiological studies suggest that chronic alcoholics are at
risk of viral infections. Clinical and basic research has demonstrate
d that alcohol not only worsens the natural history of chronic viral h
epatitis, but also seems to interact with the Viral replication cycle
leading to an unusual serum virological profile and/or modification in
the serum concentration of viral particles. infections with hepatitis
B and C viruses are a major risk for the development of hepatocellula
r carcinoma in excessive drinkers who should he protected against thes
e viruses.