The properties of perfluorochemical liquids, particularly their high g
as solubility, enables them to be exploited in cell bio-technology. Th
ey can facilitate respiratory-gas delivery to prokaryotic and eukaryot
ic cells in culture; in some systems, they can stimulate production of
biomass, yields of commercially important cellular products and, for
plant systems, expression of totipotency. The recoverability, and henc
e recycleability, of perfluorochemicals from aqueous systems makes the
ir routine use a commercially feasible option. This article reviews th
e applications and beneficial effects of perfluorochemicals in culture
d microbial, animal and plant cells, including both aerobic and anaero
bic systems.