BIPHASIC CYANATION OF ARYL HALIDES WITH COUNTER PHASE-TRANSFER CATALYSTS

Authors
OKANO T KIJI J TOYOOKA Y
Citation
T. Okano et al., BIPHASIC CYANATION OF ARYL HALIDES WITH COUNTER PHASE-TRANSFER CATALYSTS, Chemistry Letters, (5), 1998, pp. 425-426
Citations number
25
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
5
Year of publication
1998
Pages
425 - 426
Database
ISI
SICI code
0366-7022(1998):5<425:BCOAHW>2.0.ZU;2-4
Abstract
The cyanation of aryl iodides with NaCN under heptane-water two-phase conditions is efficiently catalyzed by PdCl2{PPh2(m-C6H4SO3Na)}(2) in the presence of zinc chloride and NaBH4, and gave the corresponding ar yl nitriles in high yields. The biphasic cyanation had an advantage in that the aryl nitriles are easily separated from the mixtures of cata lyst and reagents.