A new side-projected catheter for in vivo blood flow measurements has
been developed and tested, This catheter is designed to measure blood
flow in both the forward (towards the catheter tip) and reverse (away
from the catheter tip) flow directions. It consists of two multimode o
ptical fibres with core diameter of 50 mu m and cladding diameter of 1
25 mu m. One fibre transmits the laser beam into blood and the other r
eceives the back-scattered light from the erythrocytes within the prob
e volume. The experimental plots of the dominant frequency (frequency
with the highest amplitude) against the flow velocity are found to be
linear in both the forward and reverse flow directions. This result wa
s reaffirmed by the numerical flow simulation along the fibre catheter
side wall. In the simulation, it was found that the flow within the b
oundary layer is indeed laminar, and hence the relationship between th
e Doppler shift frequencies and the flow velocities is linear, thereby
making the linear calibration possible for predicting the free stream
flow velocity. The analysis of the experimental and the computational
results indicated that the boundary layer along the side wall of the
fibre catheter varies with both the flow velocity and flow direction.
Furthermore, using the fibre optic catheter with an increasing fibre c
ore separation, it was observed experimentally and numerically that th
e percentage of the free stream flow velocity increases, suggesting th
at the projection of the measuring probe volume is indeed moving towar
ds the free stream domain. (C) 1998 Society of Photo-Optical Instrumen
tation Engineers. [S0091-3286(98)02106-0].