ENTERAL ADMINISTRATION OF LIPID EMULSIONS PROTECTS LIVER CYTOCHROME-C-OXIDASE FROM HEPATOTOXIC ACTION OF THIOACETAMIDE

Authors
CERVINKOVA Z DRAHOTA Z
Citation
Z. Cervinkova et Z. Drahota, ENTERAL ADMINISTRATION OF LIPID EMULSIONS PROTECTS LIVER CYTOCHROME-C-OXIDASE FROM HEPATOTOXIC ACTION OF THIOACETAMIDE, Physiologia bohemoslovaca, 47(2), 1998, pp. 151-154
Citations number
13
Categorie Soggetti
Physiology
Journal title
Physiologia bohemoslovaca → ACNP
ISSN journal
03699463
Volume
47
Issue
2
Year of publication
1998
Pages
151 - 154
Database
ISI
SICI code
0369-9463(1998)47:2<151:EAOLEP>2.0.ZU;2-M
Abstract
During 48 hours after application sublethal doses of hepatotoxic agent thiacetamide decrease cytochrome c oxidase activity of rat liver homo genate and isolated mitochondria to 46 % and 32 % of original values, respectively. This decrease may be prevented by simultaneous applicati on of lipid emulsion (mixture of Lipofundin and Mygliol) twice a day.