HYPERSENSIBILITY SYNDROME IN A PATIENT WI TH MYCOPLASMA-PNEUMONIAE INFECTION

Background Skin manifestations have been described in 25% of patients with Mycoplasma pneumoniae infection. Case report. We report a case of Mycoplasma pneumoniae infection in a 29-year-old man who developed a polymorphous erythema-like reaction. Skin manifestations were associat ed with voluminous lymph node enlargement and high eosinophil levels b oth in serum and alveolar lavage. Seroconverion against Mycoplasma pne umoniae IgG was documented with ELISA. The clinical course was favorab le with erythromycin. Discussion. ELISA IgG seroconversion is sufficie nt to confirm the diagnosis of Mycoplasma pneumoniae infection as this test has an 80-90% specificity. This case was unusual by its clinical presentation and high eosinophil counts in serum and tissue samples, similar to what is found in drug-induced hypersensitivity.