The main aim of this study is to characterize the effect of some comme
rcial detergents on whey proteins in order to select an efficient dete
rgent to clean inorganic membranes fouled during the process of whey p
roteins fractionation. The influence of such variables such as time, p
H, temperature, type and detergent concentration on the rate of protei
n hydrolysis has been established. Also, the nature and size of produc
ed peptides have been determined. The most efficient values of cleanin
g parameters have been obtained by using the enzymatic detergent P3-Ul
trasil 62.