EPIDEMIOLOGY OF HEPATITIS-E VIRUS IN MALE BLOOD-DONORS IN JEDDAH, SAUDI-ARABIA

To our knowledge, only a few epidemiological reports on the prevalence of hepatitis E antibodies in Saudi blood donors have been published. Men of several nationalities, donating blood at King Khalid National G uard Hospital (Jeddah, Saudi Arabia) were selected (n = 593) for this study examining the seroprevalence of hepatitis E virus (HEV) in the l ocal male donor population and testing the relationship of the antibod y to HEV (anti-HEV) to donor characteristics using Odds Ratio (OR) and Chi-square statistic. The prevalence of anti-HEV in the group examine d was 16.9 per cent (100/593), The seroprevalence for Saudi donors was 14.8 per cent compared with 33.3 per cent for non-Saudis of Middle Ea stern origin, Donors who were 40 yr and over had significantly higher seroprevalence than those donors who were 30 yr or younger (OR =2.5, p = 0.006). There was a significant association between anti-HEV and an ti-HCV with donors who were positive to anti-HCV having about 5 times the risk of HEV than those who were anti-HCV negative (p = 0.02). Thes e findings demonstrate the high seroprevalence rate of anti-HEV among male blood donors in Saudi Arabia.