PLYERS-SHAPED DIAMINES-I - 3-ENDO-AMINO-2,4-CYCLOTROPANECARBONITRILESAND 3-ENDO-AMINO-2,4-CYCLOGRANATANECARBONITRILES

Authors
VILSMAIER E HERWECK T SCHUMMEL M TETZLAFF C DOTZAUER M BERGSTRASSER U
Citation
E. Vilsmaier et al., PLYERS-SHAPED DIAMINES-I - 3-ENDO-AMINO-2,4-CYCLOTROPANECARBONITRILESAND 3-ENDO-AMINO-2,4-CYCLOGRANATANECARBONITRILES, Tetrahedron, 54(26), 1998, pp. 7401-7416
Citations number
42
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
26
Year of publication
1998
Pages
7401 - 7416
Database
ISI
SICI code
0040-4020(1998)54:26<7401:PD-3>2.0.ZU;2-S
Abstract
3-endo-Amino-2,4-cyclotropane- and 3-endo-amino-2,4-cyclogranatanecarb onitriles could be synthesized from the enamines of tropinone or pseud opelletierines by subsequent reactions with N-chlorosuccinimide and cy anide. Configuration and conformation of the tricyclic unit in the new compounds were determined by H-1 NMR spectroscopy. The plyers-like sh ape of the diamine unit was confirmed by an X-ray structural analysis. (C) 1998 Elsevier Science Ltd. All rights reserved.