H. Ogasawara et al., VERY LOW-DOSE CYCLOSPORINE TREATMENT OF STEROID-RESISTANT INTERSTITIAL PNEUMONITIS ASSOCIATED WITH SJOGRENS-SYNDROME, Clinical rheumatology, 17(2), 1998, pp. 160-162
Cyclosporin is known to be effective for both transplantation and a sp
ectrum of immune-mediated diseases. Because this agent also causes sev
ere adverse effects, especially nephrotoxicity, careful monitoring is
required for the development of such reactions. Here we report the suc
cessful treatment with extremely low-dose cyclosporin (1 mg/kg/day) of
a patient who had steroid-resistant interstitial pneumonitis and Sjog
ren's syndrome.