STANDARDIZED TECHNIQUE OF LAPAROSCOPIC SURGERY IN THE RAT

The evolution of advanced laparoscopic techniques requires animal mode ls for instrument development, evaluation of the physiopathological co rrelation and physician training. Selection of surgical models is prim arily based on cost, availability, anatomic and physiologic considerat ions, and housing and anesthetic methods. The use of large animals is becoming increasingly difficult due to restrictive legislation, public concern, and economic factors. A standardized technique of laparoscop ic surgery in the rat has been developed to perform procedures in all abdominal regions including fundoplication, splenectomy, nephrectomy, liver resection, herniorraphy, colotomy, colectomy, and retroperitonea l exploration. The equipment consists of a specially designed small an imal operating table, a standard arthroscope and micro-instruments. Th e rat model gives the opportunity to investigate the physiopathologica l relations and immune functions of laparoscopic procedures, to develo p micro-instruments under realistic conditions of a live organism, and it is an excellent training model especially for pediatric and micros urgery. Besides low costs and easy availability, the rat model require s less logistic and financial efforts.