Approximately 40 million Americans have chronic sleep disorders, the m
ost serious of which is obstructive sleep apnea, The goals of this res
earch were to serve as a demonstration project for a multicenter treat
ment outcomes research project for patients with obstructive sleep apn
ea, A clinical-severity staging system was created to control for impo
rtant differences in the severity of sleep apnea among the enrolled pa
tients. A disease-specific quality-of-life measure was used in this pr
oject to measure, from the patient's perspective, important pretreatme
nt and posttreatment physical, functional, and emotional aspects of ob
structive sleep apnea, Adults with apnea indexes greater than 5 who ha
d not previously undergone uvulopalatoplasty were eligible. In total 1
42 patients were enrolled from eight otolaryngology practices, The mea
n age was 48 years, 112 were men, and 114 were white, The mean pretrea
tment apnea index was 40.0, and the mean respiratory distress index wa
s 60.5. Seventy-one patients received continuous positive airway press
ure, and 48 patients received surgery, Outcomes were assessed from sco
res on patient-based general and disease-specific health status measur
es 4 months after enrollment. The short duration of follow-up and limi
ted number of patients undergoing posttreatment polysomnograms prohibi
t any analysis of treatment effectiveness. Nevertheless, this research
represents a step forward for the support of future outcomes research
projects by organized otolaryngology.