A. Kawano et al., INTRACOCHLEAR FACTORS CONTRIBUTING TO PSYCHOPHYSICAL PERCEPTS FOLLOWING COCHLEAR IMPLANTATION, Acta oto-laryngologica, 118(3), 1998, pp. 313-326
The performance of cochlear implant patients may be related to intraco
chlear, histopathological factors. We have performed detailed post-mor
tem examinations of five human, implanted cochleas and for each electr
ode correlated the psychophysical threshold, comfortable level and dyn
amic range with spiral ganglion cell survival, presence of fibrous tis
sue and/or new bone, and distance between the centers of the electrode
bands and Rosenthal's canal. The psychophysical parameters were stron
gly interrelated. Threshold and comfort levels correlated with the dis
tance between the electrodes and Rosenthal's canal. Threshold levels a
lso correlated with the presence of intracochlear fibrous tissue and n
ew bone, especially with the former. The dynamic range showed a negati
ve correlation with intracochlear pathology, especially with new bone.
Comfort levels and dynamic range were related to spiral ganglion cell
survival. The distance between the electrodes and the modiolus increa
sed with increasing levels of fibrous tissue and new bone. Spiral gang
lion cell survival was decreased with increasing levels of fibrous tis
sue and new bone.