This study evaluated the impact of alcohol drinking habits on mortalit
y in Italy during the 1980-1990 period. Alcohol Attributable Fractions
for a list of Alcohol-Related Diseases were assessed from national an
d international medical literature and then applied to national mortal
ity data according to 5 y age groups, sex, and place of residence for
each year of the 1980-1990 period. Mortality rates and 95% Confidence
Intervals were standardized with the direct method. Years of potential
life lost (YPLL) were calculated for 1990. 18 033 Italian residents d
ied during 1990 from causes related to alcohol drinking, representing
3.3% of general mortality (males 4.6%; females 2.0%) which corresponde
d to over 200 000 YPLL up to age 70 y. Chronic diseases account for 65
% of alcohol-related mortality. Age-adjusted death rates declined in b
oth genders during 1980-1990. Geographic differences in death rates ar
e well evident. Alcohol drinking is a strong determinant of mortality
in Italy. The variability of alcohol-related death rates across the co
untry and the comparison with the results from other populations sugge
st that health consequences, mainly liver damage, of alcohol intake in
Italy may be affected by other factors than alcohol itself. The need
for further methodological efforts to improve alcohol attributable fra
ction estimates is recommended.