Two patients suffering from SUNCT syndrome are presented. Some feature
s are remarkable. The first patient was a 69-year-old man whose first
crisis was located in the right supraorbital region. After a 4-month s
pontaneous remission. the pain returned to the upper part of the cheek
, radiating to the supraciliary region on the same side, with lacrimat
ion and conjunctival injection. Rhinorrhea was absent. The painful att
acks were triggered by head movements. Clinical improvement occurred w
ith carbamazepine treatment. The second patient was a 48-year-old woma
n whose painful attacks lasted from 30 to 45 seconds followed by a bur
ning sensation lasting 2 hours. Autonomic signs such as conjunctival i
njection, lacrimation, and edema and ipsilateral ptosis of the upper l
id were rather marked. There was never any rhinorrhea. Her attacks wer
e triggered by head and eye movements. She responded to the administra
tion of corticosteroids and carbamazepine. According to these features
, the two patients had SUNCT syndrome, and the positive carbamazepine
response suggests a relationship with trigeminal neuralgia.