Coupled channels calculations of the fusion cross sections for O-16 wi
th an aligned Ho-165 target are presented. Predictions are made for th
e orientation dependence that would be observed in an experiment and t
hese are compared with previous predictions. We predict that in an exp
eriment, aligning the target will change an unpolarized cross section
of order 1Omb by between 40% and 175%, depending on the experimental c
onditions. The coupled channels results are compared with the results
of eigenchannel and semiclassical methods.