[2.2]PHANEPHOS-RUTHENIUM(II) COMPLEXES - HIGHLY-ACTIVE ASYMMETRIC CATALYSTS FOR THE HYDROGENATION OF BETA-KETOESTERS

Authors
PYE PJ ROSSEN K REAMER RA VOLANTE RP REIDER PJ
Citation
Pj. Pye et al., [2.2]PHANEPHOS-RUTHENIUM(II) COMPLEXES - HIGHLY-ACTIVE ASYMMETRIC CATALYSTS FOR THE HYDROGENATION OF BETA-KETOESTERS, Tetrahedron letters, 39(25), 1998, pp. 4441-4444
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
25
Year of publication
1998
Pages
4441 - 4444
Database
ISI
SICI code
0040-4039(1998)39:25<4441:[C-HAC>2.0.ZU;2-V
Abstract
The application of the planar chiral [2.2]PHANEPHOS ligand in the Ru(I I)-catalyzed asymmetric hydrogenation of beta-ketoesters gave up to 96 % ee involving a practical and reproducible procedure using the define d and readily prepared [2.2]PHANEPHOS-Ru(II)bis(trifluoroacetate) salt in the presence of a halide source. (C) 1998 Elsevier Science Ltd. Al l rights reserved.