DIRECT FORMATION OF 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE FROM 1-DEOXY-D-XYLULOSE 5-PHOSPHATE BY 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, A NEW ENZYME IN THE NON-MEVALONATE PATHWAY TO ISOPENTENYL DIPHOSPHATE

Authors
KUZUYAMA T TAKAHASHI S WATANABE H SETO H
Citation
T. Kuzuyama et al., DIRECT FORMATION OF 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE FROM 1-DEOXY-D-XYLULOSE 5-PHOSPHATE BY 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, A NEW ENZYME IN THE NON-MEVALONATE PATHWAY TO ISOPENTENYL DIPHOSPHATE, Tetrahedron letters, 39(25), 1998, pp. 4509-4512
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
25
Year of publication
1998
Pages
4509 - 4512
Database
ISI
SICI code
0040-4039(1998)39:25<4509:DFO24F>2.0.ZU;2-T
Abstract
1-Deoxy-D-xylulose 5-phosphate is biotransformed to 2-C-methyl-D-eryth ritol 4-phosphate in a single step in die presence of NADPH by a new r ecombinant enzyme named I-deoxy-D-xylulose 5-phosphate reductoisomeras e purified from Escherichia coli. (C) 1998 Elsevier Science Ltd. All r ights reserved.