DIASTEREODIFFERENTIATING COUPLING OF PHENOXY RADICAL MOIETY CONTROLLED BY 2,4-PENTANEDIOL TETHER - PREPARATION OF OPTICALLY-ACTIVE PUMMERERS KETONE ANALOGS

Authors
YAMAGUCHI K SUGIMURA T NISHIDA F TAI A
Citation
K. Yamaguchi et al., DIASTEREODIFFERENTIATING COUPLING OF PHENOXY RADICAL MOIETY CONTROLLED BY 2,4-PENTANEDIOL TETHER - PREPARATION OF OPTICALLY-ACTIVE PUMMERERS KETONE ANALOGS, Tetrahedron letters, 39(25), 1998, pp. 4521-4524
Citations number
32
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
25
Year of publication
1998
Pages
4521 - 4524
Database
ISI
SICI code
0040-4039(1998)39:25<4521:DCOPRM>2.0.ZU;2-1
Abstract
The highly diastereo-differentiating coupling of the phenoxy radical c ould be achieved by a 2,4-pentanediol tethered reaction to give a sing le diastereomer of Pummerer's ketone analog. By the removal of the chi ral auxiliary, the optically active phenoxy radical dimer was obtained in good yield. (C) 1998 Elsevier Science Ltd. All rights reserved.