A TAENIA-SOLIUM ONCOSPHERE PROTEIN HOMOLOGOUS TO HOST-PROTECTIVE TAENIA-OVIS AND TAENIA-SAGINATA 18 KDA ANTIGENS

Authors
GAUCI CGP FLISSER A LIGHTOWLERS MW
Citation
Cgp. Gauci et al., A TAENIA-SOLIUM ONCOSPHERE PROTEIN HOMOLOGOUS TO HOST-PROTECTIVE TAENIA-OVIS AND TAENIA-SAGINATA 18 KDA ANTIGENS, International journal for parasitology, 28(5), 1998, pp. 757-760
Citations number
13
Categorie Soggetti
Parasitiology
Journal title
International journal for parasitology → ACNP
ISSN journal
00207519
Volume
28
Issue
5
Year of publication
1998
Pages
757 - 760
Database
ISI
SICI code
0020-7519(1998)28:5<757:ATOPHT>2.0.ZU;2-N
Abstract
A Taenia solium cDNA (TSOL-18) encoding a protein with close homology to host protective oncosphere antigens from Taenia ovis (To18) and Tae nia saginata (TSA-18) is described here. TSOL-18 was cloned from mRNA obtained from hatched and activated oncospheres of T. solium. The high level of predicted amino acid sequence homology among TSOL-18 and oth er host protective taeniid antigens suggests that the protein expresse d by TSOL-18 may be capable of being used as a vaccine against T. soli um infection in the parasite's intermediate hosts. (C) 1998 Australian Society for Parasitology. Published by Elsevier Science Ltd.