CROSS-AXIS COIL PLANET CENTRIFUGE FOR THE SEPARATION AND PURIFICATIONOF POLAR COMPOUNDS

A new counter-current chromatograph, named the cross-axis coil planet centrifuge, has been optimized through various versions since 1987. Fe atures of this recently commercialized apparatus are reviewed. It allo ws the use of biphasic polar solvent systems, of aqueous solutions of polymers and systems containing an organic phase of small or moderate hydrophobicity. Separations and purifications achieved on the cross-ax is device demonstrate that it provides a good efficiency and resolutio n with very high retention of the stationary phase at convenient flow- rates, whatever the solvent system used.