Background: Digital photoplethysmography is used to assess hemodynamic
variability and baroreflex sensitivity. Numerous studies have critica
lly evaluated the accuracy of the photoplethysmographic device against
peripheral pressure. The aim of our study was to compare finger blood
and aortic root pressure. Methods: We prospectively compared simultan
eous recordings of systolic pressure at the aortic root and finger lev
el over three consecutive respiratory cycles in 15 patients (56+/-11 y
ears) undergoing routine cardiac catheterization, Data were obtained a
t baseline, during deep breathing maneuver (0.1 Hz), and after left ve
ntricular cineangiography. Results: At baseline, systolic finger press
ure overestimated systolic aortic pressure (145.2+/-22.5 vs 115.0+/-20
.1 mm Hg; p<0.001). The pressure difference (30.2+/-17.0 mm Hg) was no
t influenced. by systolic aortic pressure. There was no relationship b
etween pressure difference and the main determinants of the pulse wave
amplification phenomenon. There was a bent-to-beat relationship betwe
en finger and aortic pressure in 14 of 15 subjects (slope ranging from
0.37 to 1.70; ordinate: from -58 to +98 mm Hg), During the deep breat
hing maneuver and after left ventricular cineangiography, finger press
ure still overestimated aortic pressure by 32.3+/-15.0 mm Hg and 38.3/-13.9 mm Hg, respectively teach p<0.001), There was a beat-to-deat re
lationship between systolic aortic root pressure (IAoBP) and systolic
finger (FBP) in 13 of 15 patients, with major scattering of both slope
s and ordinates. Throughout the study, there was no predictable relati
onship between the level of IAoBP and pressure bias. Conclusions: As e
xpected, FBP was almost always higher than IAoBP. Importantly, the dif
ferences in systolic pressure did not correlate with known determinant
s of the pulse wave amplification phenomenon. The device must be used
cautiously if one wants to noninvasively track spontaneous or induced
changes in IAoBP.