POLYTRIFLUOROSTYRENE-COATED SILICA AS A PACKING FOR COLUMN LIQUID-CHROMATOGRAPHY

A reversed-phase hydrolytically stable packing material prepared by ch emisorption of a trifluorostyrene-containing copolymer on to the surfa ce of porous silica was tested by high-performance liquid chromatograp hy of various aromatic compounds. It was found that the polytrifluoros tyrene (PTFS) phase has an intermediate adsorption activity between th ose of polytetrafluoroethylene and polystyrene phases. A high selectiv ity of PTFS-coated silica in the separation of haloaryl compounds was observed. Wide-pore silica coated with PTFS was found to give an effic ient resolution of peptides and proteins.